Kanav Kahol Website

Research: Neurological Rehabilitation

Research Synopsis

Hemi-spatial neglect is a neural disorder produced by a lateralized disruption of spatial attention. It essentially manifests in the patients being unable to perceive one side of their sensory field (generally left). Several efforts have been made towards rehabilitation of neglect. However many of these tasks are not neurologically inspired and do not target areas of lesions specifically. At CUbiC, we are involved in an interdisciplinary and collaborative research with Barrows Neurological Institute (BNI) Phoenix towards development of multimodal visio-haptic virtual reality environments that are geared towards rehabilitation of hemi-spatial neglect. Our approach has firm basis in the neurological findings that propose that (a), hemi-spatial neglect is a attentional disorder, (b) it is caused by damage to the attentional network whici=h includes parietal cortex-the area of multimodal integration. I am a co-collaborator on this project with Priyamvada Tripathi and Dr. Leslie Baxter as the Principal investigator's.

Research Summary

Our aim is to develop neural rehabilitation systems for hemi-spatial neglect. We propose to use multimodal virtual reality based simulations that will pose tasks involving various modalities and hence may lead to faster and more effective rehabilitation. It is hypothesized that rehabilitation of hemispatial neglect can be achieved by the use of the multimodal, adaptive, and context-aware virtual reality system.
My contribution to this research is at theoretical as well as implementational level in terms of haptics. Priyamvada Tripathi designed the system and formulated the basis for the system. The following paragraphs explain the conceptual framework that guides this research.

Hemispatial neglect is a disorder marked by patient’s inattention of hemi-space contralateral to the lesion in the brain. For example, patients with lesions in the right hemisphere of the brain fail to attend to the information in the left visual or tactile hemi-space and vice-versa. Research has shown that neglect is a post-sensory disorder. It has been found that neglect patients typically sense the environmental stimuli but fail to process the information. This is a debilitating condition resulting in impairment of self-care (dressing, eating) and restricts patients from driving and other daily activities. Currently, rehabilitation of neglect involves paper-pencil based tasks such as drawing and cancellation. Few attempts have been made to translate these tasks to virtual reality (VR) environments. However, both paper pencil tasks, and current VR tasks have failed to show encouraging results in the performance of patients. While the patients did show minor improve on the rehabilitation tasks, their performance remained unchanged in the activities of daily living (ADL). Hence, it is imperative that new rehabilitation tasks are designed which actively engage patients and target a better carry-over effect to ADL.
Designing rehabilitation tasks in VR should involve an understanding of the anatomical basis of neglect and its behavioral manifestation. Virtual reality environments present an exciting opportunity to immerse the patients in tasks that involve multiple modalities and engage the attentional network in the brain more effectively than the conventional paper-pencil tasks. This research proposes a VR based system with cognitive retraining tasks for patients with hemispatial neglect that involve multi-modal coordination.

Research Approach

I designed the virutal reality setup and one of the tasks for this experiments. he system has three components: a) visual and haptic feedback component comprising of a computer screen and two CyberTouch® haptic gloves b) electromagnetic Ascension® Trackers for measuring hand movements and c) an interactive management software that acts as the central control engine for the execution and management of the sessions. Additionally, the system stores environmental variable, session variables, and profiles of the patient. Together the gloves, trackers, and display form a visio-haptic feedback loop.
Each rehabilitation session consists of two set of tasks involving varying level of cognitive load. The first task is a program for cancellation of 3D objects. In this task, different shapes such as circles and squares are presented on the screen. The patient is instructed to ‘cancel’ or remove the item of the requested shape by touching it with the virtual hand and feeling a vibrotactile feedback. Scores are recorded for each task. After each task, performance is evaluated on the basis of these scores and reaction times. In the modified version, haptic cueing is incorporated into the system to encourage performance. If the subject has omitted the shapes in certain hemisphere, valid visual and haptic cue is provided indicating the spatial location he/she should pursue. A screenshot of this simulation is shown in Figure 1.


Figure 1. Cancellation Task in virtual Reality

The Video for a sample interaction is available here.

The second task was the tracking task which I proposed and designed. In this task a patient is requested to track a ball moving in the space. As soon as the patient catches the ball it moves to a new location. The motivation is provided by visual feedback and tactile feedback when the user touches the ball. The trajectory of the ball is configurable and we can vary it depending on the condition of the patient. Cueing is incorporated into the system to guide the user when needed to explore the neglected side of the visual field. While cancellation is essentially adapted from paper-pencil task, the tracking task is a novel task proposed by our team. Figure 2 shows a snapshot of the system.

Figure 2. Tracking Simulation

A Video of the tracking interaction is available here .

We are currently developing a third simulation that involves a story-telling task with gesture recognition. I have implemented the gesture recognition tasks, the virtual reality simulation.

Publications

P Tripathi, K Kahol, L Baxter, T McDaniel, A Baker and S Panchanathan," Rehabilitation of patients with hemispatial neglect using visual-haptic feedback in virtual reality environment ", accepted for publication at International Conference on Human-Computer Interfaces to be held in Las Vegas, May 2005

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